Signalling

Part:BBa_K511500

Designed by: Grant Robinson   Group: iGEM11_MIT   (2011-09-27)


pDisplay-Vasopressin-MYC Ligand MammoBlock

This part encodes a novel fusion protein that serves to display the arginine vasopressin hormone in the extracellular space of a mammalian cell. This protein consists of the transmembrane domain of the platelet-derived growth factor receptor, the sequence for arginine vasopressin, and the sequence for the MYC epitope. This synthetic ligand was designed for juxtacrine signaling to the arginine vasopressin receptor (AVPR) class, and was specifically designed to function with the AVPR2-TEVs-Gal4-VP16 construct.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
n/apDisplay-Vasopressin-MYC Ligand MammoBlock